Almost all cultures in the world have been insisting on eating less and observing periodic fasting for religious regions but now a group of scientists have confirmed in the laboratory that it is good practice with health benefits:
Scientists at University of Southern California observed that the fasting mimicking diet promotes the growth of new beta cells in the pancreas that are responsible for producing insulin which leads to reduction in the symptoms of type 1 and type 2 diabetes in mice. Some of this phenomenon was observed in human beta cells growing in petri-dish as well.
"Cycles of a fasting-mimicking diet and a normal diet essentially reprogrammed non-insulin-producing cells into insulin-producing cells," said Dr. Valter Longo, who is director of the Longevity Institute at the USC Leonard Davis School of Gerontology. Dr. Longo, further said - "By activating the regeneration of pancreatic cells, we were able to rescue mice from late-stage type 1 and type 2 diabetes. We also reactivated insulin production in human pancreatic cells from type 1 diabetes patients."
"These findings warrant a larger FDA trial on the use of the fasting-mimicking diet to treat human diabetes patients to help them produce normal levels of insulin while improving insulin function," Dr. Longo said. "Hopefully, people with diabetes could one day be treated with an FDA-approved fasting-mimicking diet for a few days each month and gain control over their insulin production and blood sugar."
However, this study does not mean that patients with diabetes should start trying fasting mimicking diet without any clinical supervision. This study is still in early stages and your doctor will tell you whether or not FDA, and if yes, when will start any clinical trial. Dr. Logo warned the patients: "In regard to our recent studies on diabetes, DO NOT try to apply any type of fasting mimicking diet (FMD) to treat either type 1 or type 2 diabetes either on your own or with the help of a doctor. The combination of the FMD and insulin or other drugs could increase the risk of severe complications, including the possibility of death. Although the use of the FMD to treat either type 1 or 2 diabetes is promising, it must be tested and proven safe and effective for human use in FDA-approved clinical trials."
http://www.cell.com/cell/fulltext/S0092-8674(17)30130-7?_returnURL=http%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0092867417301307%3Fshowall%3Dtrue
Scientists at University of Southern California observed that the fasting mimicking diet promotes the growth of new beta cells in the pancreas that are responsible for producing insulin which leads to reduction in the symptoms of type 1 and type 2 diabetes in mice. Some of this phenomenon was observed in human beta cells growing in petri-dish as well.
"Cycles of a fasting-mimicking diet and a normal diet essentially reprogrammed non-insulin-producing cells into insulin-producing cells," said Dr. Valter Longo, who is director of the Longevity Institute at the USC Leonard Davis School of Gerontology. Dr. Longo, further said - "By activating the regeneration of pancreatic cells, we were able to rescue mice from late-stage type 1 and type 2 diabetes. We also reactivated insulin production in human pancreatic cells from type 1 diabetes patients."
"These findings warrant a larger FDA trial on the use of the fasting-mimicking diet to treat human diabetes patients to help them produce normal levels of insulin while improving insulin function," Dr. Longo said. "Hopefully, people with diabetes could one day be treated with an FDA-approved fasting-mimicking diet for a few days each month and gain control over their insulin production and blood sugar."
However, this study does not mean that patients with diabetes should start trying fasting mimicking diet without any clinical supervision. This study is still in early stages and your doctor will tell you whether or not FDA, and if yes, when will start any clinical trial. Dr. Logo warned the patients: "In regard to our recent studies on diabetes, DO NOT try to apply any type of fasting mimicking diet (FMD) to treat either type 1 or type 2 diabetes either on your own or with the help of a doctor. The combination of the FMD and insulin or other drugs could increase the risk of severe complications, including the possibility of death. Although the use of the FMD to treat either type 1 or 2 diabetes is promising, it must be tested and proven safe and effective for human use in FDA-approved clinical trials."
http://www.cell.com/cell/fulltext/S0092-8674(17)30130-7?_returnURL=http%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0092867417301307%3Fshowall%3Dtrue
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